I have an ASP.Net 2.0 form that uses Teleriks RadServiceManager to call a web service in the same application. All was working fine, but when I deployed it to another machine, the web service calls failed. I checked the Event Log and found something like this:

Request format is unrecognized for URL unexpectedly ending in '/ArtifactSearch/'. 

Googling turned up this helpful article. Apparently, web service calls using HTTP GET and POST are disabled by default on 1.1 installations, and I guess that can linger in machine.config or somewhere, and even though my app was a 2.0 app, it inherited these settings. You can enable the calls by adding this to the <system.web> section of your apps web.config: 

<webServices>

  <protocols>

    <add name="HttpGet"/>

    <add name="HttpPost"/>

  </protocols>

</webServices>

That did the trick for me!